Paper recorded by Signals 4 on 2026-11-03 in cs.LG. Abstract reproduced from arXiv; link to the original below.
Published 2026-11-03 on arXiv · recorded by Signals 4 on 2026-11-04
Category: cs.LG · 机器学习 · first seen 2026-11-04
De novo peptide sequencing has moved from dynamic programming over hand-designed or generative scores to large transformers that learn the task end to end. We present NovoCRF, a conditional random field (CRF) whose states are prefix masses, so that its paths are exactly the peptides within +/-0.06 Da of the precursor mass. A small network scores each edge from physics-derived ion-match features an